Speaking on Fox News The Five, the American TV presenter attacked Mr De Blasio as he blamed the popular news channel for «negativity and divisiveness» in the USA.
In an interview with British newspaper The Guardian, the New York City Mayor said America would be «more unified» if media tycoon News Corp was removed from the last 25 years of American history.
Mr De Blasio claimed the US «would not be suffering a lot of the negativity and divisiveness we’re going through right now».
But the Fox News presenter had the perfect response for the «leftie» Democrat.
You can’t beat lefties for burdening humanity and that’s why ‘Lurch’ hates us
Mr Gutfeld said: “Bill De Blasio, when was the last time you gave this towering piece of politics a thought?
“So he thinks America would be better off without us?
“What he’s really saying is he would be better off without us, but he’s wrong.
“Even without America’s most watched news channel making fun of him other progressives still shun him.
“He’s 7ft of political invisibility.
“So it should be easy that De Blasio’s dumb ideas don’t exist but if that were the case millions of people would be better off.
“You can’t beat lefties for burdening humanity and that’s why ‘Lurch’ hates us.
“We point this out while doing our best to ignore him.»